A suspected chlorine gas attack on an underground hospital in the rebel-held north of Syria’s Hama governorate killed three people, including a surgeon, and injured dozens more.
As rebels infiltrated Damascus in a surprise attack, defense of the city was joined by Hezbollah al-Nujaba, an Iraqi Shi'ite militia under command of Iranian Revolutionary Guards.
The UN Food and Agriculture Organization warned that the Middle East and North Africa risk becoming uninhabitable in a few decades, with water reserves falling dramatically.
The US air-lifts Kurdish fighters into ISIS territory in preparation for a final assault on Raqqa—while bombing the city, deepening the growing enmity between Kurds and Arabs.
The Kurdish YPG militia says it has agreed to establishment of a Russian military base in its territory, although Moscow calls it a "reconciliation center."
The US is denying reports that it bombed a mosque in northwestern Syria during evening prayers, killing at least 50—despite mounting evidence from survivors and witnesses.
Two federal judges—one in Maryland and another in Hawaii—issued temporary restraining orders against President Trump's new 90-day travel ban.
Killings, forced recruitment and other grave violations against children in Syria were the highest on record in 2016, said UNICEF in a grim assessment as the war reaches six years.
A new Qaeda affiliate in Syria has claimed responsibility for a double bomb attack targeting Shi'ite pilgrims near a shrine in Damascus that killed at least 40 Iraqis.
The Pentagon is dispatching some 2,500 combat troops to back up forces fighting the Islamic State in Iraq and Syria, as the US-led anti-ISIS coalition continues to fracture.
Massachusetts has joined Washington, Hawaii, Oregon, and New York in suing to block President Trump's revised travel ban as unconstitutional under the Equal Protection clause.
Amid shifting alliances in the scramble for northern Syria, Kurdish-led forces are accused of handing over territory to the Assad regime, in a deal brokered by Russia.
